Methandienone (also known as methandrostenolone, Dbol, dianabol) is an orally-effective anabolic steroid originally developed in Germany and released in the US in the early 1960s by Ciba Specialty Chemicals. This is a derivative from testosterone, one of the most popular steroid compounds in the world and the second steroid (after testosterone) ever produced. Methandienone promotes dramatic increases in protein synthesis, glycogenolysis, and muscle strength over a short space of time.
Cardiovascular risk factors include the alteration or diminishing of glucose tolerance and hyperinsulinism, which means becomes resistant to insulin , or a change in lipoproteins, which means carrying cholesterol in the blood, a fraction of which can cause cardiovascular disease and atherosclerosis, deposition of fatty substances onto inner walls of arteries causing blockage. These increased triglyceride levels, can cause hypertension, abnormally high blood pressure, or changes in her myocardium, middle muscular layer of the heart wall, and increased concentration levels of several different clotting factors. Cardiomyopathy, a typical chronic disorder of the heart muscle, which may involve hypertrophy and obstructive damage to the heart, myocardial infarction which is the localized death of the myocardium tissue usually leading to heart failure, heart attack, stroke, and cerebro-vascular accidents have all been causes in deaths where AAS abuse was implicated. Of course the liver, the body’s primary filtration system will come under attack as it has to accommodate the increased toxicity. Among the liver problems promoted are holestatic jaundice, which is failure of bile flow that causes yellowish pigmentation of skin, tissues, and body fluids, peliosis hepatic, blood-filled cysts that develop on liver, hepatocellular hyperplasia, unusual increase of an epithelial parenchymatous cell called hepatocytes in the liver, and cancer. Secondary filters such as the kidneys and gallbladder also become more susceptible to disease.