Another disadvantage is that all steroids (not only oral) inhibit hypothalamus-pituitary-testicular axis (HPTA) and endogenous testosterone production. For this reason, you should not take oral steroids solo. You probably know that almost all steroids are derived from our native androgen testosterone. However, these derivatives are no longer native to our body. Hence, testosterone shall always be used in stack with oral steroids to maintain normal physiological functions of the body during the cycle. Furthermore, as mentioned above, oral steroids have a feature to reduce SHBG levels, which means that the efficiency of testosterone stacked with tablets will raise significantly.
The Mesterolone hormone is not estrogenic. It does not aromatize and it carries no progestin nature. As a result, the side effects of Proviron will not include any related effects such as gynecomastia or excess water retention. Such adverse effects are impossible with this steroid. This will also greatly reduce the risk of high blood pressure as high blood pressure associated with anabolic steroid use is often due to extreme water retention. In fact, Proviron should provide an anti-estrogenic effect by preventing testosterone to estrogen conversion or at least tremendously slow it down.