The side effects of Masteron Enanthate can and primarily surround those of an androgenic nature. The androgenic side effects of Masteron Enanthate may include acne, hair loss in men predisposed to male pattern baldness and body hair growth. Despite a potent binding relationship to the androgen receptor the total androgenic activity should not be extreme and such side effects should not be extreme. If you are predisposed to male pattern baldness this steroid is well known for speeding up hair loss and should be avoided if that is a concern. If you are not predisposed hair loss is impossible.
Important Note: the 5-alpha reductase enzyme, the enzyme that reduces testosterone to DHT, does not metabolize Drostanolone. There is no reduction; it’s already DHT. Because no reduction exists there is nothing to inhibit or block and this means 5-alpha reductase inhibitors like Finasteride will do nothing to combat androgenic effects.
Masteron Enanthate can also promote virilization symptoms in women. Virilization refers to the promotion of male characteristics in women, specifically body hair growth, a deepening of the vocal chords and clitoral enlargement. It is very possible to use this steroid without these issues, although genetic sensitivity will play a role. If symptoms begin to show simply discontinue use and they will rapidly go away. It is when virilization symptoms are allowed to set in that they become a problem and in some cases irreversible.
Important note: Female users of Drostanolone will be best served by choosing Drostanolone Propionate as it will clear the body faster should issues arise.
Within bodybuilding, weight lifting and other sports communities, the use of Drostanolone propionate is valued for its assistance in building harder muscle mass and increasing overall muscle density. As a result, the androgenic steroid is particularly desirable among individuals looking to improve their overall muscular strength without “bulking up” excessively or increasing muscle mass. In addition, the use of Drostanolone propionate is popular among bodybuilding enthusiasts, as regular use of the steroid can create a more chiseled physique by helping to build denser musculature.
Like other AAS, drostanolone is an agonist of the androgen receptor (AR).  It is not a substrate for 5α-reductase and is a poor substrate for 3α-hydroxysteroid dehydrogenase (3α-HSD), and therefore shows a high ratio of anabolic to androgenic activity.  As a DHT derivative, drostanolone is not a substrate for aromatase and hence cannot be aromatized into estrogenic metabolites .  While no data are available on the progestogenic activity of drostanolone, it is thought to have low or no such activity similarly to other DHT derivatives.  Since the drug is not 17α-alkylated , it is not known to cause hepatotoxicity . 
In bodybuilding, Drostanoloneis especially popular for its properties: the drug has a diuretic effect, thereby achieving the best relief and vascularity and muscle definition. Drostanolone is valued by athletes who want to increase the density and hardness of the muscles, often used in the run-up to the competition. You can achieve excellent muscle look, due to the lipolytic effect of the drug. As practice shows, the administration rate of Drostanoloneis able to reduce body weight by 6-8% of the original, which is an excellent result (without the use of growth hormone and peptides).