Methandienone is an anabolic steroid banned from use by FDA under controlled substances act. Dianabol has been very popular in bodybuilders until its ban to increase strength and volume of their muscles. Dianabol acts strongly on androgen receptors and exerts its effects by protein synthesis and glycogen breakdown to increase muscle mass in short space of time. Dianabol produces estrogen as end product so water retention is also one of the contributors towards weight gain and increased volume. Dianabol effective dose is15-50 mg/day in men and its active life is 6-8 hours. Dianabol is excreted through kidneys and detection time in urine is 5-6 weeks. Until the ban Dianabol has been used as tonic by bodybuilders. Probably, Dianabol is effective in treatment of senile postmenopausal osteoporosis. Dianabol was also recommended in those individuals who are suffering from condition called pituitary deficient dwarfism. Dianabol was also used in those individuals who have weakened bones and always complain for exhaustion after small running and prolong walking. Still, Dianabol is prepared in large quantity in those countries where drugs regulations are weak and is used in human as well as in veterinary patients of the conditions described above.
Dianabol is not an extremely androgenic steroid, its androgenicity has been structurally reduced, but androgenic side effects are still possible. Such side effects of Dianabol use include acne, accelerated hair loss in those predisposed to male pattern baldness and body hair growth. Most men should not have a problem with such effects, response will be the final dictator, but most will remain clear. Although the odds are in your favor, such effects are brought on by Methandrostenolone being metabolized by the 5-alpha reductase enzyme. This is the same enzyme responsible for the reduction of testosterone to dihydrotestosterone, but the overall conversion here will result in very low amounts of dihydromethandrostenolone. This tells us 5-alpha reductase inhibitors like Finasteride that are often used to combat androgenic side effects will have very little if any affect on Dianabol.
Despite its reduced androgenicity, Dianabol can promote virilization symptoms in women. Such symptoms include body hair growth, a deepening of the vocal chords and clitoral enlargement. It is possible for some women to use this steroid without virilization symptoms with extremely low doses, but the odds are not favorable. Most all women should choose anabolic steroids with less translating androgenic activity to meet their needs.